CEBPB DAMPENS THE CUPROPTOSIS SENSITIVITY OF COLORECTAL CANCER CELLS BY FACILITATING THE PI3K/AKT/MTOR SIGNALING PATHWAY

CEBPB dampens the cuproptosis sensitivity of colorectal cancer cells by facilitating the PI3K/AKT/mTOR signaling pathway

Conveyor Toasters Background: Cuproptosis is a novel pathway that differs from other forms of cell death and has been confirmed to be applicable for predicting tumor prognosis and clinical treatment response.However, the mechanism underlying the resistance of colorectal cancer (CRC) to cuproptosis at the molecular level has not been elucidated.Meth

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Estimating the efficacy of community-wide use of systemic insecticides in dogs to control zoonotic visceral leishmaniasis: A modelling study in a Brazilian scenario.

Systemic insecticides in dogs have been suggested as a public health intervention to prevent human cases of Zoonotic Visceral Leishmaniasis (ZVL).But, currently there are no systemic insecticides for dogs registered against zoo-anthropophilic pool blood feeding phlebotomine flies.We predict the impact of community-wide use of systemic insecticide i

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RUSSIAN AUTOCRACY IN THE WORKS OF RUSSIAN CONSERVATIVE THINKERS

In the article there is considered the evolution of views on autocracy formed in the Slavophile and Eurasian school.Therewith, the appeared in the mid XIX century SOD Slavophiles think that a state in Russia is preferable to be a monarchy.Developing certainly many Slavophile ideas after 1917 in the European emigration, the representatives of the Eu

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Intraoperative and postoperative short-term outcomes of intracorporeal anastomosis versus extracorporeal anastomosis in laparoscopic right hemicolectomy

BackgroundIntracorporeal anastomosis (IA) is a difficult but popular anastomotic approach for reconstruction of digestive tract after laparoscopic right hemicolectomy, which may reduce some limitations faced during extracorporeal anastomosis (EA).MethodsA retrospective review of Girls Easter Dress 78 patients who underwent laparoscopic right hemico

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